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Generic Name: Doxepin Capsules (DOX-e-pin)
Brand Name: Sinequan
Antidepressants may increase the risk of suicidal thoughts
or actions in children, teenagers, and young adults. However,
depression and certain other mental problems may also increase
the risk of suicide. Talk with the patient's doctor to be
sure that the benefits of using Doxepin outweigh the risks.
Family and caregivers must closely watch patients who take
Doxepin. It is important to keep in close contact with the
patient's doctor. Tell the doctor right away if the patient
has symptoms like worsened depression, suicidal thoughts,
or changes in behavior. Discuss any questions with the patient's
doctor.
Doxepin is used for:
Treating depression or anxiety in certain patients. It may
also be used for other conditions as determined by your doctor.
This medicine is a tricyclic antidepressant. It is not known
exactly how it works. It may increase the activity of certain
chemicals in the brain, which help elevate mood.
Do NOT use Doxepin if:
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you are allergic to any ingredient in Doxepin
or to other tricyclic antidepressants |
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you have certain prostate problems (eg, asymptomatic
prostatic hypertrophy), glaucoma, or trouble urinating
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you are taking clonidine, an H1 antagonist (eg, astemizole,
terfenadine), or ibutilide, or you have taken a monoamine
oxidase inhibitor (MAOI) (eg, furazolidone, phenelzine,
isocarboxazid) within the past 14 days |
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Contact
your doctor or health care provider right away if any
of these apply to you. |
Before using Doxepin:
Some medical conditions may interact with Doxepin . Tell your
doctor or pharmacist if you have any medical conditions, especially
if any of the following apply to you:
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if you are pregnant, planning to become
pregnant, or are breast-feeding |
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if you are taking any prescription or nonprescription
medicine, herbal preparation, or dietary supplement |
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if you have allergies to medicines, foods, or other
substances |
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if you have a history of heart problems, seizures (eg,
epilepsy), overactive thyroid, prostate problems (eg,
benign prostatic hypertrophy [BPH]), blood problems (eg,
porphyria), other mental or mood problems, suicidal thoughts
or attempts, or alcohol abuse |
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Some MEDICINES
MAY INTERACT with Doxepin . Tell your health care provider
if you are taking any other medicines, especially any
of the following: |
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Antiarrhythmics (eg, quinidine, propafenone, flecainide),
antifungal medicines (eg, fluconazole, terbinafine), carbamazepine,
cimetidine, mibefradil, phenothiazines (eg, chlorpromazine,
thioridazine), or selective serotonin reuptake inhibitors
(SSRIs) (eg, fluoxetine, sertraline) because they may
increase the risk of Doxepin 's side effects |
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Anticoagulants (eg, warfarin), H1 antagonists (eg, astemizole,
terfenadine), ibutilide, sulfonylureas (eg, tolazamide,
glipizide), sympathomimetics (eg, phenylephrine, pseudoephedrine),
or tramadol because the risk of their side effects may
be increased by Doxepin |
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Clonidine, guanadrel, guanethidine, or guanfacine because
their effectiveness may be decreased by Doxepin |
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MAOIs (eg, furazolidone, phenelzine, isocarboxazid)
because severe toxic effects may occur |
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This may
not be a complete list of all interactions that may
occur. Ask your health care provider if Doxepin may
interact with other medicines that you take. Check with
your health care provider before you start, stop, or
change the dose of any medicine. |
How to use Doxepin:
Use Doxepin as directed by your doctor. Check the label on
the medicine for exact dosing instructions.
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Doxepin comes with an extra patient information
sheet called a Medication Guide. Read it carefully. Read
it again each time you get Doxepin refilled. |
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Take Doxepin by mouth with or without food. |
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Taking Doxepin at bedtime may help reduce side effects
(eg, daytime drowsiness). Discuss this possibility with
your doctor. |
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If you miss a dose of Doxepin , take it as soon as possible.
If it is almost time for your next dose, skip the missed
dose and go back to your regular dosing schedule. Do not
take 2 doses at once. If you take 1 dose daily at bedtime,
do not take the missed dose the next morning. |
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Ask your
health care provider any questions you may have about
how to use Doxepin. |
Important safety information:
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Doxepin may cause drowsiness, dizziness,
blurred vision. These effects may be worse if you take
it with alcohol or certain medicines. Use Doxepin with
caution. Do not drive or perform other possibly unsafe
tasks until you know how you react to it. |
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Doxepin will add to the effects of alcohol and other
depressants. Ask your pharmacist if you have questions
about which medicines are depressants. |
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Doxepin may cause dizziness, lightheadedness, or fainting;
alcohol, hot weather, exercise, or fever may increase
these effects. To prevent them, sit up or stand slowly,
especially in the morning. Sit or lie down at the first
sign of any of these effects. |
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Limit your alcohol consumption while taking Doxepin. |
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Children, teenagers, and young adults who take Doxepin
may be at increased risk for suicidal thoughts or actions.
Watch all patients who take Doxepin closely. Contact the
doctor at once if new, worsened, or sudden symptoms such
as depressed mood; anxious, restless, or irritable behavior;
panic attacks; or any unusual change in mood or behavior
occur. Contact the doctor right away if any signs of suicidal
thoughts or actions occur. |
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Doxepin may cause you to become sunburned more easily.
Avoid the sun, sunlamps, or tanning booths until you know
how you react to Doxepin . Use a sunscreen or wear protective
clothing if you must be outside for more than a short
time. |
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Tell your doctor or dentist that you take Doxepin before
you receive any medical or dental care, emergency care,
or surgery. |
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After you start taking Doxepin , several weeks may pass
before you feel the full benefit. |
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Use Doxepin with caution in the ELDERLY; they may be
more sensitive to its effects. |
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Doxepin should not be used in CHILDREN younger than
12 years old; safety and effectiveness in these children
have not been confirmed. |
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PREGNANCY and BREAST-FEEDING: If you become pregnant,
contact your doctor. You will need to discuss the benefits
and risks of using Doxepin while you are pregnant. Doxepin
is found in breast milk. Do not breast-feed while taking
Doxepin. |
Possible side effects of Doxepin:
All medicines may cause side effects, but many people have
no, or minor, side effects. Check with your doctor if any
of these most COMMON side effects persist or become bothersome:
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Appetite loss; constipation; diarrhea; dizziness;
drowsiness; dry mouth; excess sweating; headache; heartburn;
increased appetite; indigestion; nausea; unpleasant taste;
urinary retention; vomiting; weakness; weight gain. |
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Seek medical
attention right away if any of these SEVERE side effects
occur: |
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Severe allergic reactions (rash; hives; itching; difficulty
breathing; tightness in the chest; swelling of the mouth,
face, lips, or tongue); abnormal movements; aggressive
or bizarre behavior; agitation; anxiety; blurred vision
or other vision changes; chest pain; difficulty speaking
and swallowing; disorientation; eye pain; fainting; fast,
slow, or irregular heartbeat; hair loss; hallucinations;
hostility; irritability; loss of balance; mood swings;
nervousness or restlessness; panic attacks; ringing in
the ears; seizures; shakiness; sore throat or fever; trouble
sleeping; twitching of the face or tongue; unusual bleeding
or bruising; yellowing of the skin or eyes. |
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